Review : use of functional assays for the study of human coding and noncoding SNVs. Doug FowlerDecember 29, 2022sequence–function studies, functional assays, genetic variation, variant effect mapping, multiplexed assays of variant effect
"Probing the genetic code and impacts of mistranslation using tRNAAla anticodon variants" Doug FowlerDecember 8, 2022
"IsobaricQuant-- Powerful new toolkit for multiplexed proteomics!" Doug FowlerOctober 25, 2022quantitativeproteomics, MassSpec, softwaretool
New Preprint "Proteostasis governs differential temperature sensitivity across embryonic cell types" Doug FowlerAugust 15, 2022
Promising Young Scientist Florence Chardon: ‘Determined and Focused’ on Overcoming Challenges in Genomics Doug FowlerJune 22, 2022
CMAP team presents work at the Mutational Scanning Symposium Doug FowlerJune 15, 2022FunctionalGenomics, mutationalscanning, secreted proteins, Optical Screening, genome, proteomics
5th annual mutational scanning symposium set for June in Toronto! CMAP’s Doug Fowler is one of the Keynote speakers. Doug FowlerMay 16, 2022
‘Closing the Gap’ Paper Examines BBI’s Progress Toward Resolving Genetic Variants of Unknown Significance Doug FowlerFebruary 19, 2022
Monitoring viral mutations Doug FowlerJanuary 27, 2022BloombergQuicktake, pandemic, mutation, pandemic tech dev, preparedness
Dr. Doug Fowler: Q&A on NHGRI’s Bold Predictions for Human Genomics by 2030 Doug FowlerOctober 2, 2021
Assessing computational variant effect predictors via a prospective human cohort Doug FowlerOctober 2, 2021varianteffect, REVEL, VARITY, computational variant effect predictors
"Shifting landscapes of human MTHFR missense-variant effects" Doug FowlerAugust 18, 2021FunctionalAssay, varianteffectmapping, mutationalscanning, molecular dynamics
