Center Team

Douglas FOwler, director

Doug is an Associate Professor of Genome Sciences and Bioengineering at the University of Washington. He uses his expertise in protein science, genomics and computational approaches to develop new methods, particularly for understanding genetic variation.

Stanley Fields, faculty (Chair of Genome Sciences)

Stan is Professor and Chair of Genome Sciences and William H. Gates III Endowed Chair in Biomedical Sciences at the University of Washington. His lab's focus is on technology development, particularly as applied to the analysis of protein function.

Lea Starita, faculty

Lea is a Research Assistant Professor in the Genome Sciences department at the University of Washington and co-director of the Advanced Technology Lab at the Brotman Baty Institute for Precision Medicine where she develops massively parallel methods to determine the effects of genetic variation on protein function. Using this approach, she hopes to help solve the problem of variants of uncertain significance by scoring the pathogenic potential of genetic variants before they are found in the clinic.

Frederick (Fritz) Roth, Faculty

Fritz leads a team jointly located at the University of Toronto and Sinai Health System. His group continues to make fundamental contributions to genetic and protein interaction mapping, while having a major focus on developing and applying technology to systematically test the function of human sequence variants.

Judit Villén, Faculty

Judit is an Associate Professor of Genome Sciences at the University of Washington. She develops proteomics methods to study how genetic and post-translational modifications to protein sequences impact protein structure and function.

Christine Queitsch, Faculty

Christine is an Associate Professor of Genome Sciences at the University of Washington. She draws on her expertise in protein folding, gene regulation, and evolutionary genetics to think of new ways to ascertain the functional consequences of genetic variation in coding and regulatory DNA.

jay shendure, faculty

Jay is an Investigator of the Howard Hughes Medical Institute and a Professor of Genome Sciences at the University of Washington. His lab focuses on the development and application of novel technologies in genetics and genomics.

Cole Trapnell, Faculty

Cole is an Associate Professor of Genome Sciences at the University of Washington. He has a background in computer science and is the principal developer of several widely used open-source software tools for analyzing high-throughput sequencing experiments. His lab group focuses efforts on stem cell differentiation, reprogramming and cell-cell communication with the goal of developing technologies to help identify genes that regulate these processes.